Relevant and even prescient commentary on news, politics and the economy.

hydroxychloroquine and Remdesivir Update

I have repeatedly argued that, based on in vitro evidence, hydroxychloroquine should be prescribed while we wait for the results of clinical trials. Such results were just published. They are very disappointing. The link is to an LA Times Article: 2020-04-17 malaria-drugs-fails-to-help-coronavirus-patients-in-controlled-studies On the other hand Early peek at data on Gilead coronavirus drug […]

Economic Policy for the Pandemic III What About Aggregate Demand ?

Unemployment has shot up in many countries especially including the USA. Is it time for aggregate demand stimulus ? One interesting thing (noted by Krugman in his newsletter which should still be a blog) is that Keynesians (including Krugman) are not treating everything as a nail, because all they have is a hammer. He (and […]

Remdesivir V

This is interesting. In addition to the two huge multi center phase III trials of Remdesivir for Covid 19 with estimated completion some time in May 2020, there is a smaller but very large trial in Beijing with estimated completion May 1 2020. The East is Remd ! May Day May Day May Day “Estimated […]


I am back complaining about the FDA as I have in The Ethics of Clinical Trials and 10 years earlier Clinical Trial Ethics (an aside — I had forgotten the old post and Google reminded me that I have been banging this drum for a decade). Now I have a lot of company, because of […]

Remdesivir IV

This post is not up to the standards of the New England Journal of Medicine Compassionate Use of Remdesivir for Patients with Severe Covid-19 is an important article written and published with amazing speed. The (many) authors (including professional writers) assess the experience of 53 “patients who received remdesivir during the period from January 25, […]

Remdesivir III

I told you so on March 2 2020 The first Covid 19 case diagnosed in New Jersey Around 3 a.m. on March 10, Balani arrived at the hospital. The medicine had come in, and she did not want to wait until the morning to administer it. With Balani in the room, a nurse woke Cai […]

Coronavirus Thoughts

I’m not even going to try to organize this post. I am in self quarantine 6 days after having either the mildest cold I can remember or a mild case of Covid 19 (this means alone in an Air BnB away from my family too). The pattern is the same I have read about countless […]