Since this is off topic for AngryBear I will post future CAR posts at my personal blog Robert’s Stochastic thoughts This post is a restatement and extension of the first post in the series CAR Crazy which discusses ex vivo treatment of killer T-cells with Chimeric Antigen Receptors (CAR) designed to cause the T-cells to […]
Below I discussed Chimeric Antigen Receptor (CAR) T-cells and also pulled up a reply by Linda Eissenberg which taught me a lot. CAR T-cells are killer T-cells genetically modified to kill cells to which an antibody binds. I promised crazier ideas in later posts. One was the idea of further genetic modification of CAR T-cells. […]
Pulled up from a comment by Linda Eissenberg the community has been exploring them [CAR crazy ideas] for some time. For example, in the “Gene edited CAR-T” method section of this paper (Cooper, et al. https://pmc.ncbi.nlm.nih.gov/articles/PMC6102094/), T cells were treated with IL2 and IL15 before putting the CAR gene into the T cells. This work was […]
Here CAR stands for Chimeric Antigen Receptor and refers to CAR killer T-cells which are cells genetically engineered to kill other cells which display something detectable (and antigen) typical of a type of cancer. The crazy refers to my dream of improving CARs using the knowlsege from my long ago BA in biology. The amazing […]
The effort to evaluate NGOs and aid policies scientifically seems very important to me. I think there has been (long ago) a reluctance to perform experiments with people even if the experiment consists of helping some people and comparing them to a control group. The experimental approach has become very fashionable with a Nobel memorial […]
One Hour until the dread January 20th. 23 hours into the strange TikTok banned January 19th. Trump says he will delay the law banning TikTok by executive order. Can he do that???? Don’t ask me. I’m not a lawyer. However, I do have a first amendment right to play a lawyer on the web. Do […]
It really happened. Screen shot at 00:06 January 19 2025
I write 15 hours before the TikTok ban. I know almost exactly nothing about Tik Tok (I just installed the app as an act of … well it might not be available the day after tomorrow). I know almost nothing about social media or modern tech. That never stopped me before. The story is that […]
The Russians are using an amazing approach to drone warfare in Ukraine — fiber optic controlled drones. They are avoiding radio detection and jamming by using drones which play out and communicate through an optical fiber. “Russian forces are using explosive-packed drones connected to their operators by fiber-optic cables to deliver unjammable precision strikes on […]
The title is a warning to me. The claim that “this time it’s different” is supposed to be typical of bubbles, but I write it meaning it. I think that this huge increase in the relative price of housing is different. In the past such an increase has been a reliable sign of a bubble. […]