Here we are in a presidential election year, and one of the two major party candidates certain to get the nomination is still claiming the last one was stolen from him. Now, he refers to the criminals who were tried, convicted and sentenced to prison over their Jan 6 crimes as “hostages.” When did the […]

As a career research scientist, I’ve made many predictions in my time. It was fun and rewarding to design controlled experiments to test my predictions. And the wonderful thing about science is that, if your prediction is wrong, you learn something new. I don’t make many predictions myself these days. But I’m interested in the […]

I got my BA from the University of Tennessee-Knoxville in 1977. At the time, the university charged no tuition, but “fees” were about $165/quarter for a full load. Of course, as a state university, it was heavily subsidized by state tax dollars. Quite a feat for a state that has no income tax. The business […]

I’ve only voted for a Republican once (John Anderson, in a presidential primary in North Carolina), but if I lived in Vermont, I might vote for Republican governor Phil Scott: “Many point to his steady hand during crises, including last summer’s historic flooding and the pandemic, when he appeared in daily, low-key televised briefings to […]

Remember the wildly successful Trump University? Me neither. But elect Donald, and he promises to build on that success by stealing the endowments of major universities to create a national diploma mill. Click the link. Trump University 2.0

Eugenics is the practice of arranging reproduction within a human population to increase the occurrence of heritable characteristics regarded as desirable. Setting aside who gets to decide which human traits are desirable and undesirable, we simply don’t know enough about the genetic basis for things like industriousness, fidelity, thrift, honesty and countless other human behaviors […]

On our trip to Colorado for Thanksgiving, the boarding announcements for each flight began with an invitation to active service people and veterans to board first, always followed with “thank you for your service.” People join the military for many reasons. Some out of a sense of patriotism, others because that was the best-paying job […]

In the film, “The Princess Bride,” Wally Shawn repeatedly exclaims “inconceivable.” Finally, Mandy Patinkin (as Inigo Montoya) replies: “You keep using that word. I do not think it means what you think it means.” Whenever GOP politicians announce their belief that the age for Social Security and Medicare Benefits should be raised, the mainstream media […]

I’ve always done basic research. I’ve never done any research specifically aimed at a clinical goal. I’ve never patented anything I’ve done. None of that motivated my curiosity. I’ve been a medical school professor for over 36 years and was Principal Investigator on three NIH grants and one from the American Cancer Society, and I […]

The Boston Globe has an article announcing the imminent approval of Casgevy, a CRISPR-based treatment for sickle cell disease that has already been approved in Britain. It is hard to overstate how transformative CRISPR has been for genetics research, and how promising it is for gene therapy. Sickle cell disease was always the low-hanging fruit, […]