Relevant and even prescient commentary on news, politics and the economy.

Whatever happened to MOOCs?

10-15 years ago, Massive Online Open Courses (MOOCs) were a higher education fad. Universities could dispense with physical (lecture halls, heating, cooling, cleaning, security) and administrative (room scheduling) costs and just teach students online. During this period, I was associate dean for research and the Dean of our medical school brought up the suggestion that […]

How do you solve a problem like George Santos?

Can he be recalled? NoCan he be charged with a crime for lying about his bio? NoCan the House of Representatives refuse to seat him? No However: He can face criminal and civil fraud charges for lying on documents submitted to government entities and investors.He could be extradited to Brazil to face criminal charges there.He […]

Saving Ryan

I just finished reading “Saving Ryan” by Emil Kakkis. Kakkis is a physician who pioneered enzyme replacement therapy for Mucopolysaccharidosis I (MPS I), a progressive and fatal disease. The story is about the patients and their families who struggle with the disease and Emil’s struggle to deliver life-enhancing therapy against terribly long odds. The Ryan […]

Not One Inch

Just finished “Not One Inch: America, Russia, and the making of a postwar stalemate” by Mary Sarotte. The book was recommended to me by Bruce Cochrane. It is an excellent insight into current events in Ukraine today. The title comes from the assurance given by then-Secretary of State James Baker to Mikhail Gorbachev that German […]

From the frontiers of viral immunology

Ever since the COVID mRNA vaccines (Moderna and Pfizer) proved themselves, I became convinced they are the future of viral vaccines. Looks like a polyvalent flu vaccine is in the works that may obviate annual strain-specific vaccines. “In this work, we developed a nucleoside-modified messenger RNA (mRNA)–lipid nanoparticle vaccine encoding hemagglutinin antigens from all 20 […]

Africa, a biography

Just finished “Africa, A Biography of a Continent”” by John Reader. I don’t recall how this book came into my possession. It may have been on my mom’s bookshelf when we stopped by after they moved to take whatever we wanted. Whatever its provenance, I had only read a little African history: “King Leopold’s Ghost” […]

Review of “Demagogue”

Review of “Demagogue” “Demagogue: The life and long shadow of Senator Joe McCarthy” by Larry Tye is a particularly timely read as the nation continues in the grip of another political bully, Donald Trump. The parallels in their methods are striking and the degree to which McCarthy held the nation in thrall during the 1950s […]

Review of “Superfuel”

Growing up in Oak Ridge TN in the ‘60s, terms like “homogeneous reactor,” “molten salt reactor” and “breeder reactor” were frequently used, although I couldn’t have explained them at the time. Research into nuclear power became the mission of Oak Ridge National Labs after the war under the direction of Alvin Weinberg. A few years […]