Relevant and even prescient commentary on news, politics and the economy.

Immune Memory

One non horrible effect of the Covid 19 epidemic is that people have become interested in immunology. I am pleased by this, but have the sense that journalists over-simplify. Roughly they act as if the immune system consists of circulating antibodies and killer t-cells. I think this post might be of some interest to some […]

Get A Booster shot

Many months and many mutations ago, I argued that one shot of the Pfizer/BioNTech vaccine was enough to protect against the original Sars Cov2. Since then delta. It doesn’t especially evade, but is more generally fit and I thought (and probably didn’t post) that two shots are needed given delta. Now omicron. Pfizer just claimed […]

The Biden Administration had better come up with a ‘Plan B’

Coronavirus dashboard for December 7: since further mass vaccination could only happen at gunpoint, the Biden Administration had better come up with a ‘Plan B, New Deal democrat No significant economic news today, so let’s catch up a little bit with Covid. There are still distortions in the 7 day average data, as States did […]

A Day of Days

Wednesday, 1 December 2021, the state of Mississippi argued before the US Supreme Court that the 1973 Roe vs Wade decision [410 U.S. 113 (1973)] giving women a constitutional right to have an abortion was in error; that it should be overturned. During Wednesday’s oral arguments, Justice Sotomayor asked Mississippi’s Solicitor Stewart whether Mississippi’s challenge […]

Omicron at Slow Boring

I think every word of Matthew Yglesias’s post on Omicron, Omar Bradley, and why the hell aren’t we investing in pandemic prevention is brilliant. I think it is publicly available (I didn’t pay) and advise just clicking the link. For those who ignored the above advice, I would like to focus on two main points […]

Half of what you read about Omicron is wrong, but you won’t know which half for weeks

Coronavirus dashboard for November 29: half of what you read about Omicron is wrong, but you won’t know which half for weeks, New Deal democrat As with any “Breaking News!” event, about half of what you read will be wrong. The problem is, nobody knows which item falls in which half. Recognizing that you need to step […]

Moderna’s Intellectual Property

Robert Waldmann has some questions and thoughts! Hi Robert, AB upgraded the way we post now. (run75441). I am going to ask someone to engage your post who has far greater knowledge than I or anyone else has. He is a Professor of Biochemistry & Molecular Biology and participated in the Moderna clinical trials. I […]

Explaining Mutations and Variants

Blogger and Commenter Professor Joel Essenberg addresses Covid variants being called mutations. As a geneticist, I am troubled by the promiscuous use of the word “mutation” to describe amino acid or nucleotide differences from a reference sequence. In nearly all cases, there is no known functional significance attached to these differences. Accordingly, the differences are […]

Pessimistic and optimistic scenarios for the winter wave

Coronavirus dashboard for November 26: pessimistic and optimistic scenarios for the winter wave, New Deal democrat I hope all of you had a Happy Thanksgiving. Since I haven’t posted one in a bit, here is an update on the pandemic.As an initial matter, in the last day or two, there has been a mini-panic about […]

As the winter wave takes hold, how much will resistance from prior infections hold numbers down?

Coronavirus dashboard: As the winter wave takes hold, how much will resistance from prior infections hold numbers down? Europe and North America, the winter wave is underway. While vaccinations clearly work, in most countries of the West there is a reservoir of defiant anti-vaxxers, who are not going to get vaccinated unless they are absolutely […]