Keep getting those COVID jabs, peeps!

Pandemics are bad for economies. Vaccinations are an important bulwark against pandemics. But all viruses and all vaccines are not alike.

In the case of the annual flu vaccine, annual vaccination against flu variants can be a problem: antibody-producing memory cells crowd out new antibody-producing cells, and people develop relatively few neutralizing antibodies against the strains in the newer vaccine. Does getting updated COVID boosters interfere with vaccine effectiveness?

Recent data suggest that regular re-vaccination with updated COVID-19 vaccines against variants could provide protection not only from the SARS-CoV-2 variants represented in the vaccines, but also other SARS-CoV-2 variants and related coronaviruses, possibly including ones that have not yet emerged.

“The study, available online in Nature, shows that people who were repeatedly vaccinated for COVID-19 — initially receiving shots aimed at the original variant, followed by boosters and updated vaccines targeting variants — generated antibodies capable of neutralizing a wide range of SARS-CoV-2 variants and even some distantly related coronaviruses. The findings suggest that periodic re-vaccination for COVID-19, far from hindering the body’s ability to recognize and respond to new variants, may instead cause people to gradually build up a stock of broadly neutralizing antibodies that protect them from emerging SARS-CoV-2 variants and some other coronavirus species as well, even ones that have not yet emerged to infect humans.”

repeated COVID vaccination enhances broad immunity